CO2 challenge induced HPA axis activation in panic
نویسندگان
چکیده
منابع مشابه
HPA Axis Activity under Psychosocial Stress in Patients with Acute and Remitted Panic Disorder
Background: Panic disorder (PD) has been linked to an altered activity of Hypothalamic-pituitary-adrenal (HPA) axis. To understand the elevated risk for future psychiatric episodes in PD it is of interest how remitted patients might differ from healthy controls in the activity of the HPA axis. Methods: Fourteen patients with PD and 14 healthy controls were exposed to the Trier Social Stress Tes...
متن کاملHPA axis activity in patients with panic disorder: review and synthesis of four studies.
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis may play a role in panic disorder. HPA studies in patients with panic disorder, however, have produced inconsistent results. Seeking to understand the inconsistencies, we reexamined endocrine data from four studies of patients with panic disorder, in light of animal data highlighting the salience of novelty, control, and social supp...
متن کاملHPA axis-rhythms.
The hypothalamic-pituitary-adrenal (HPA) axis regulates circulating levels of glucocorticoid hormones, and is the major neuroendocrine system in mammals that provides a rapid response and defense against stress. Under basal (i.e., unstressed) conditions, glucocorticoids are released with a pronounced circadian rhythm, characterized by peak levels of glucocorticoids during the active phase, that...
متن کاملSalivary cortisol in panic: are males more vulnerable?
OBJECTIVES The underlying mechanisms of panic attacks (PA's) are still unclear. Theories focusing on these mechanisms differ in their description of the relationship between panic and fear. The main controversy concerns whether a PA resembles the classical flight response, or whether it is qualitatively different from fear. According to the first theory, a PA would result in hypothalamic-pituit...
متن کاملStress and the HPA Axis
Stress has long been suggested to be an important correlate of uncontrolled drinking and relapse. An important hormonal response system to stress-the hypothalamic-pituitary-adrenal (HPA) axis-may be involved in this process, particularly stress hormones known as glucocorticoids and primarily cortisol. The actions of this hormone system normally are tightly regulated to ensure that the body can ...
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ژورنال
عنوان ژورنال: The International Journal of Neuropsychopharmacology
سال: 2006
ISSN: 1461-1457,1469-5111
DOI: 10.1017/s1461145706007358